Evonik silica for Pharmaceutical
Why silica matters in pharma formulation
Silica excipients play a central role in solid dosage forms, supporting both processability and finished product performance. Depending on grade and morphology, Evonik silicas can:
- Improve powder flow and dosing accuracy
- Enhance tablet hardness and reduce variability
- Support continuous manufacturing concepts
- Increase stability and moisture control
- Improve dissolution of poorly soluble APIs
These functionalities make silica a true multipurpose excipient rather than a simple processing aid
Overview of Pharma-grade silica portfolio
Evonik Pharma-grade silicas are produced in line with IPEC-GMP guidelines and comply with major pharmacopoeia monographs. They are characterised by high chemical purity, low elemental impurity levels and comprehensive quality documentation, supported by auditability and long-standing use as pharmaceutical excipients.
| Product | Primary function | Typical application focus | Key characteristics |
| AEROSIL® 200 Pharma | Glidant | Powder flow and tableting | Industry-standard glidant supporting consistent powder flow, dosing and tablet properties, acting as a central excipient for homogeneous and stable tablets in continuous direct compression |
| AEROSIL® 200 VV Pharma | Glidant | Handling and logistics optimisation | Same functionality as AEROSIL® 200 Pharma with higher density and reduced dust |
| AEROSIL® 300 Pharma | Glidant / performance enhancer | Mechanically stable tablets | Higher surface area supporting enhanced tablet strength |
| AEROSIL® R 972 Pharma | Hydrophobic glidant | Moisture-sensitive formulations | Hydrophobic surface for moisture protection and flow efficiency |
| AEROPERL® 300 Pharma | Carrier Dissolution enhancement | Solubility and bioavailability enhancement | Granulated, mesoporous silica enabling liquid adsorption and dissolution improvement |
Discover our highlight products
AEROSIL® 200 Pharma
Evonik's proven pharmaceutical glidant designed to optimise powder flow, dosing accuracy and tablet consistency in batch and continuous direct compression processes.
AEROPERL® 300 Pharma
Evonik’s mesoporous high absorptive carrier silica is designed to improve dissolution and bioavailability of poorly water-soluble APIs (e.g., BCS class II and IV) while enabling free-flowing powders and robust solid dosage forms.
